EUTOS Score for Chronic Myeloid Leukaemia: Clinical Guide

Overview

Calculates EUTOS risk from spleen size and basophil percentage.

Clinical Significance

A score above 87 defines high risk in the original model.

When to Use

• Use as decision support when all required inputs are reliable.

How It Is Calculated

• EUTOS = 7×basophils (%) + 4×spleen size (cm).

Interpretation

• A score above 87 defines high risk in the original model.

Worked Example

Enter verified values in the displayed units; MedicalC applies the published equation or point system.

Limitations

• Prediction models may be miscalibrated outside their derivation population.
• Measurement and classification error can materially change the result.

Clinical Pearls

• Document source values and units with the result.
• Use trends and the full clinical picture.

Common Mistakes

• Wrong units.
• Using non-contemporaneous inputs.
• Treating the output as a diagnosis or mandatory treatment decision.

References

1. Hasford J et al. Blood. 2011;118:686-692. — Primary or supporting reference for the implemented model.