DAS28 ESR Disease Activity Score Calculator

Calculates rheumatoid arthritis disease activity from 28-joint counts, ESR and patient global health. Includes interpretation, information buttons and a clinical guide.

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DAS28 ESR Disease Activity Score
Clinical Decision Tool

Calculates rheumatoid arthritis disease activity from 28-joint counts, ESR and patient global health.

Enter the clinically verified value.
Enter the clinically verified value.
Enter the clinically verified value.
Enter the clinically verified value.
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Clinical Decision Support Only

MediCalc calculators are intended to support qualified healthcare professionals and must not replace professional clinical judgement. Do not enter patient-identifiable information into Saved Progress.

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MedicalC Knowledge Hub

DAS28 ESR Disease Activity Score: Clinical Guide

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Calculates rheumatoid arthritis disease activity from 28-joint counts, ESR and patient global health.

Overview

Calculates rheumatoid arthritis disease activity from 28-joint counts, ESR and patient global health.

Clinical Significance

DAS28-ESR below 2.6 suggests remission; 2.6–3.2 low, >3.2–5.1 moderate and >5.1 high disease activity.

When to Use

  • Use as structured clinical decision support when the required data are available and reliable.

How It Is Calculated

  • The displayed variables are combined using the published equation or weighted point system.

Interpretation

  • DAS28-ESR below 2.6 suggests remission; 2.6–3.2 low, >3.2–5.1 moderate and >5.1 high disease activity.

Worked Example

Enter verified patient data in the displayed units; MedicalC applies the published equation or point system.

Limitations

  • Classification and prognostic tools can be misapplied outside their validated population.
  • Missing, estimated or non-contemporaneous data may materially change the result.

Clinical Pearls

  • Document the input values, units, date and clinical setting with the result.
  • Use serial scores only when the same instrument and measurement method are used consistently.

Common Mistakes

  • Using the tool without confirming entry criteria.
  • Selecting overlapping findings that should be represented by the highest-scoring item only.
  • Treating a classification threshold as a standalone diagnosis.

Frequently Asked Questions

What does this tool calculate?

Calculates rheumatoid arthritis disease activity from 28-joint counts, ESR and patient global health.

Can this result be used alone?

No. Interpret it with the complete clinical assessment, applicable entry criteria and current guidance.

References

  1. Prevoo MLL et al. Arthritis Rheum. 1995;38:44-48. — Primary or supporting reference for the implemented model.

Reviewed by: MedicalC Clinical Editorial Team
Last reviewed: July 2026

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Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026

Clinical Disclaimer

MedicalC calculators and clinical tools are intended to support healthcare professionals. They do not replace clinical judgement, individual patient assessment, local guidance or specialist advice.

Results should always be interpreted in the context of the patient’s history, examination, investigations, current clinical condition and applicable professional guidance.

Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026
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