CLIF-C Acute Decompensation Score: Clinical Guide

Overview

Estimates mortality in acutely decompensated cirrhosis without ACLF.

Clinical Significance

Higher scores indicate greater short-term mortality in acute decompensation; use alongside ACLF assessment and specialist review.

When to Use

• Use as structured clinical decision support when the required data are available and reliable.

How It Is Calculated

• The displayed variables are combined using the published equation, decision rule or weighted point system.

Interpretation

• Higher scores indicate greater short-term mortality in acute decompensation; use alongside ACLF assessment and specialist review.

Worked Example

Enter verified patient data in the displayed units; MedicalC applies the published model.

Limitations

• Risk and classification tools can be misapplied outside their validated population.
• Missing, estimated or non-contemporaneous data may materially change the result.

Clinical Pearls

• Document the input values, units, date and clinical setting with the result.
• Use serial scores only when the same instrument and measurement method are used consistently.

Common Mistakes

• Using the tool without confirming entry criteria.
• Using approximate or incorrectly converted laboratory values.
• Treating a prognostic score as a standalone treatment decision.

References

1. Jalan R et al. J Hepatol. 2015;62:831-840. — Primary or supporting reference for the implemented model.