Full Age Spectrum Cystatin C eGFR: Clinical Guide

Overview

Estimates eGFR using the Full Age Spectrum cystatin C equation.

Clinical Significance

Requires an appropriate cystatin C Q value and standardised assay.

When to Use

• Use as decision support when all required inputs are reliable.

How It Is Calculated

• eGFR = 107.3/(cystatin C/Q), multiplied by 0.988^(age−40) after age 40.

Interpretation

• Requires an appropriate cystatin C Q value and standardised assay.

Worked Example

Enter verified values in the displayed units; MedicalC applies the published equation or point system.

Limitations

• Prediction models may be miscalibrated outside their derivation population.
• Measurement and classification error can materially change the result.

Clinical Pearls

• Document source values and units with the result.
• Use trends and the full clinical picture.

Common Mistakes

• Wrong units.
• Using non-contemporaneous inputs.
• Treating the output as a diagnosis or mandatory treatment decision.

References

1. Pottel H et al. Nephrol Dial Transplant. 2017;32:497-507. — Primary or supporting reference for the implemented model.