Glasgow Prognostic Score (GPS): Clinical Guide

Overview

Calculates the original Glasgow Prognostic Score from CRP and albumin.

Clinical Significance

Higher scores indicate a stronger systemic inflammatory response and worse prognosis in studied cancers.

When to Use

• Use as decision support when all required inputs are reliable.

How It Is Calculated

• One point for CRP >10 mg/L and one point for albumin <35 g/L.

Interpretation

• Higher scores indicate a stronger systemic inflammatory response and worse prognosis in studied cancers.

Worked Example

Enter verified values in the displayed units; MedicalC applies the published equation or point system.

Limitations

• Prediction models may be miscalibrated outside their derivation population.
• Measurement and classification error can materially change the result.

Clinical Pearls

• Document source values and units with the result.
• Use trends and the full clinical picture.

Common Mistakes

• Wrong units.
• Using non-contemporaneous inputs.
• Treating the output as a diagnosis or mandatory treatment decision.

References

1. Forrest LM et al. Br J Cancer. 2003;89:1028-1030. — Primary or supporting reference for the implemented model.