HFA–PEFF Diagnostic Score Calculator

Supports assessment of heart failure with preserved ejection fraction using functional, morphological and biomarker domains. Includes information buttons, interpretation and a Knowledge Hub clinical guide.

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HFA–PEFF Diagnostic Score
Clinical Decision Tool

Supports assessment of heart failure with preserved ejection fraction using functional, morphological and biomarker domains.

Enter the clinically verified value.
Enter the clinically verified value.
Enter the clinically verified value.
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Clinical Decision Support Only

MediCalc calculators are intended to support qualified healthcare professionals and must not replace professional clinical judgement. Do not enter patient-identifiable information into Saved Progress.

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MedicalC Knowledge Hub

HFA–PEFF Diagnostic Score: Clinical Guide

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Supports assessment of heart failure with preserved ejection fraction using functional, morphological and biomarker domains.

Overview

Supports assessment of heart failure with preserved ejection fraction using functional, morphological and biomarker domains.

Clinical Significance

Scores 0–1 make HFpEF unlikely, 5–6 support HFpEF, and 2–4 require functional testing.

When to Use

  • Use as decision support when all required inputs are reliable.

How It Is Calculated

  • Each domain contributes 0, 1 or 2 points; total 0–6.

Interpretation

  • Scores 0–1 make HFpEF unlikely, 5–6 support HFpEF, and 2–4 require functional testing.

Worked Example

Enter verified values in the displayed units; MedicalC applies the published equation or point system.

Limitations

  • Prediction models may be miscalibrated outside their derivation population.
  • Measurement and classification error can materially change the result.

Clinical Pearls

  • Document source values and units with the result.
  • Use trends and the full clinical picture.

Common Mistakes

  • Wrong units.
  • Using non-contemporaneous inputs.
  • Treating the output as a diagnosis or mandatory treatment decision.

Frequently Asked Questions

What does this tool calculate?

Supports assessment of heart failure with preserved ejection fraction using functional, morphological and biomarker domains.

Can the result be used alone?

No. Interpret it with the complete clinical assessment and current guidance.

References

  1. Pieske B et al. Eur Heart J. 2019;40:3297-3317. — Primary or supporting reference for the implemented model.

Reviewed by: MedicalC Clinical Editorial Team
Last reviewed: July 2026

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Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026

Clinical Disclaimer

MedicalC calculators and clinical tools are intended to support healthcare professionals. They do not replace clinical judgement, individual patient assessment, local guidance or specialist advice.

Results should always be interpreted in the context of the patient’s history, examination, investigations, current clinical condition and applicable professional guidance.

Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026
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