HFA–PEFF Diagnostic Score: Clinical Guide

Overview

Supports assessment of heart failure with preserved ejection fraction using functional, morphological and biomarker domains.

Clinical Significance

Scores 0–1 make HFpEF unlikely, 5–6 support HFpEF, and 2–4 require functional testing.

When to Use

• Use as decision support when all required inputs are reliable.

How It Is Calculated

• Each domain contributes 0, 1 or 2 points; total 0–6.

Interpretation

• Scores 0–1 make HFpEF unlikely, 5–6 support HFpEF, and 2–4 require functional testing.

Worked Example

Enter verified values in the displayed units; MedicalC applies the published equation or point system.

Limitations

• Prediction models may be miscalibrated outside their derivation population.
• Measurement and classification error can materially change the result.

Clinical Pearls

• Document source values and units with the result.
• Use trends and the full clinical picture.

Common Mistakes

• Wrong units.
• Using non-contemporaneous inputs.
• Treating the output as a diagnosis or mandatory treatment decision.

References

1. Pieske B et al. Eur Heart J. 2019;40:3297-3317. — Primary or supporting reference for the implemented model.