Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.
Overview
Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.
Clinical Significance
A prognostic index developed in advanced lung cancer and studied in other conditions. Cut-offs vary and should not be universalised.
How It Is Calculated
- ALI = BMI × albumin / NLR.
Interpretation
- A prognostic index developed in advanced lung cancer and studied in other conditions. Cut-offs vary and should not be universalised.
Worked Example
Enter a clinically consistent set of values in the displayed units. MedicalC applies: ALI = BMI × albumin / NLR.
Limitations
- This tool does not establish a diagnosis or mandate treatment.
- Published cut-offs may vary between cohorts and measurement methods.
- Calculation precision cannot compensate for poor source data.
Clinical Pearls
- Trend the result over time where clinically appropriate.
- Record the source values and units alongside the calculated result.
Common Mistakes
- Using the wrong unit.
- Combining measurements obtained at different times.
- Applying a research-derived threshold as a universal treatment trigger.
Frequently Asked Questions
What does this calculator provide?
Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.
Can this result be used alone?
No. It must be interpreted with clinical context and appropriate investigations.
What equation is used?
ALI = BMI × albumin / NLR.
What is the main limitation?
The result depends on valid inputs and may not be calibrated for every population or setting.
References
- Jafri SH et al. Assessment of the inflammatory state in patients with advanced non-small cell lung cancer using ALI. Clin Med Insights Oncol. 2013. — Formula, physiological or validation reference.
Reviewed by: MedicalC Clinical Editorial Team
Last reviewed: July 2026