Khorana VTE Risk Score Calculator

Estimates venous thromboembolism risk in ambulatory patients starting systemic cancer therapy. Includes interpretation, information buttons and a clinical guide.

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Khorana VTE Risk Score
Clinical Decision Tool

Estimates venous thromboembolism risk in ambulatory patients starting systemic cancer therapy.

Select the finding that best matches the patient.
Select the finding that best matches the patient.
Select the finding that best matches the patient.
Select the finding that best matches the patient.
Select the finding that best matches the patient.
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Clinical Decision Support Only

MediCalc calculators are intended to support qualified healthcare professionals and must not replace professional clinical judgement. Do not enter patient-identifiable information into Saved Progress.

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MedicalC Knowledge Hub

Khorana VTE Risk Score: Clinical Guide

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Estimates venous thromboembolism risk in ambulatory patients starting systemic cancer therapy.

Overview

Estimates venous thromboembolism risk in ambulatory patients starting systemic cancer therapy.

Clinical Significance

Higher scores indicate greater chemotherapy-associated VTE risk.

When to Use

  • Use as structured clinical decision support when the required data are available and reliable.

How It Is Calculated

  • The displayed variables are combined using the published equation, decision rule or weighted point system.

Interpretation

  • Higher scores indicate greater chemotherapy-associated VTE risk.

Worked Example

Enter verified patient data in the displayed units; MedicalC applies the published model.

Limitations

  • Risk and classification tools can be misapplied outside their validated population.
  • Missing, estimated or non-contemporaneous data may materially change the result.

Clinical Pearls

  • Document the inputs, units, date and clinical setting with the result.
  • Use serial scores only when the same instrument and measurement method are used consistently.

Common Mistakes

  • Using the tool without confirming entry criteria.
  • Using approximate or incorrectly converted values.
  • Treating a prognostic score as a standalone treatment decision.

Frequently Asked Questions

What does this tool calculate?

Estimates venous thromboembolism risk in ambulatory patients starting systemic cancer therapy.

Can this result be used alone?

No. Interpret it with the full clinical assessment, applicable entry criteria and current guidance.

References

  1. Khorana AA et al. Blood. 2008;111:4902-4907. — Primary or supporting reference for the implemented model.

Reviewed by: MedicalC Clinical Editorial Team
Last reviewed: July 2026

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Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026

Clinical Disclaimer

MedicalC calculators and clinical tools are intended to support healthcare professionals. They do not replace clinical judgement, individual patient assessment, local guidance or specialist advice.

Results should always be interpreted in the context of the patient’s history, examination, investigations, current clinical condition and applicable professional guidance.

Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026
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