Advanced Lung Cancer Inflammation Index Calculator

Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio. Includes field guidance, formula provenance, interpretation and Learn More content.

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Advanced Lung Cancer Inflammation Index
Clinical Decision Tool

Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.

Use measured height and weight where possible.
Use albumin in g/dL.
Use an absolute count.
Use an absolute count.
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Clinical Decision Support Only

MediCalc calculators are intended to support qualified healthcare professionals and must not replace professional clinical judgement. Do not enter patient-identifiable information into Saved Progress.

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Learn More About Advanced Lung Cancer Inflammation Index
MedicalC Knowledge Hub

Advanced Lung Cancer Inflammation Index: Clinical Guide

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Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.

Overview

Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.

Clinical Significance

A prognostic index developed in advanced lung cancer and studied in other conditions. Cut-offs vary and should not be universalised.

How It Is Calculated

  • ALI = BMI × albumin / NLR.

Interpretation

  • A prognostic index developed in advanced lung cancer and studied in other conditions. Cut-offs vary and should not be universalised.

Worked Example

Enter a clinically consistent set of values in the displayed units. MedicalC applies: ALI = BMI × albumin / NLR.

Limitations

  • This tool does not establish a diagnosis or mandate treatment.
  • Published cut-offs may vary between cohorts and measurement methods.
  • Calculation precision cannot compensate for poor source data.

Clinical Pearls

  • Trend the result over time where clinically appropriate.
  • Record the source values and units alongside the calculated result.

Common Mistakes

  • Using the wrong unit.
  • Combining measurements obtained at different times.
  • Applying a research-derived threshold as a universal treatment trigger.

Frequently Asked Questions

What does this calculator provide?

Calculates the advanced lung cancer inflammation index from BMI, albumin and neutrophil-to-lymphocyte ratio.

Can this result be used alone?

No. It must be interpreted with clinical context and appropriate investigations.

What equation is used?

ALI = BMI × albumin / NLR.

What is the main limitation?

The result depends on valid inputs and may not be calibrated for every population or setting.

References

  1. Jafri SH et al. Assessment of the inflammatory state in patients with advanced non-small cell lung cancer using ALI. Clin Med Insights Oncol. 2013. — Formula, physiological or validation reference.

Reviewed by: MedicalC Clinical Editorial Team
Last reviewed: July 2026

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Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026

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Clinical Disclaimer

MedicalC calculators and clinical tools are intended to support healthcare professionals. They do not replace clinical judgement, individual patient assessment, local guidance or specialist advice.

Results should always be interpreted in the context of the patient’s history, examination, investigations, current clinical condition and applicable professional guidance.

Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026
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