Holliday–Segar Daily Maintenance Fluid Calculator

Calculates estimated daily maintenance fluid using the Holliday–Segar 100/50/20 rule. Includes formula, interpretation, limitations and references.

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Holliday–Segar Daily Maintenance Fluid
Clinical Decision Tool

Calculates estimated daily maintenance fluid using the Holliday–Segar 100/50/20 rule.

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Clinical Decision Support Only

MediCalc calculators are intended to support qualified healthcare professionals and must not replace professional clinical judgement. Do not enter patient-identifiable information into Saved Progress.

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MedicalC Knowledge Hub

Holliday–Segar Daily Maintenance Fluid: Clinical Guide

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Calculates estimated daily maintenance fluid using the Holliday–Segar 100/50/20 rule. This guide explains the formula, use and limitations.

Overview

Calculates estimated daily maintenance fluid using the Holliday–Segar 100/50/20 rule.

Clinical Significance

Maintenance estimates must be adjusted for illness, enteral intake, renal function, electrolytes and ongoing losses.

When to Use

  • Use when the calculation is relevant to the clinical question.
  • Confirm that the population and units match the validated method.
  • Use current and reliable measurements.

How It Is Calculated

  • 100 mL/kg for first 10 kg, 50 mL/kg for next 10 kg, then 20 mL/kg.

Interpretation

  • Maintenance estimates must be adjusted for illness, enteral intake, renal function, electrolytes and ongoing losses.
  • Interpret alongside the full clinical picture and current guidance.

Worked Example

Enter the required measurements in the stated units. MedicalC then applies: 100 mL/kg for first 10 kg, 50 mL/kg for next 10 kg, then 20 mL/kg.

Patient Considerations

  • Consider age, body size, pregnancy, organ function and treatment effects where relevant.
  • Repeat the calculation when inputs or clinical status materially change.

Limitations

  • Accuracy depends on the quality and units of the entered data.
  • The equation may not be validated in every patient population.
  • This tool does not replace clinical judgement or specialist advice.

Clinical Pearls

  • Check units before calculating.
  • Document the source and timing of each input.
  • Use trends where clinically appropriate.

Common Mistakes

  • Mixing SI and conventional units.
  • Using non-contemporaneous measurements.
  • Treating the output as a diagnosis or prescription.

Evidence Base

The implemented calculation follows the published or guideline-based relationship: 100 mL/kg for first 10 kg, 50 mL/kg for next 10 kg, then 20 mL/kg.

Frequently Asked Questions

What does the Holliday–Segar Daily Maintenance Fluid calculator do?

Calculates estimated daily maintenance fluid using the Holliday–Segar 100/50/20 rule.

Can the result be used alone?

No. Use it as decision support with clinical assessment and current guidance.

Why might the result be misleading?

Incorrect units, poor measurement quality or use outside the validated population can produce misleading results.

Should it be recalculated?

Recalculate when relevant measurements or the clinical condition change.

References

  1. Holliday MA, Segar WE. The maintenance need for water in parenteral fluid therapy. Pediatrics. 1957. — Primary publication, guideline or established source supporting the calculation.

Reviewed by: MedicalC Clinical Editorial Team
Last reviewed: July 2026

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Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026

Clinical Disclaimer

MedicalC calculators and clinical tools are intended to support healthcare professionals. They do not replace clinical judgement, individual patient assessment, local guidance or specialist advice.

Results should always be interpreted in the context of the patient’s history, examination, investigations, current clinical condition and applicable professional guidance.

Reviewed by: MedicalC Clinical Editorial Team Last reviewed: July 2026
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